This monograph examines the psychological correlates of tetany syndrome, a functional condition characterized by increased neuromuscular excitability that is often mistaken for panic disorder because of overlapping symptoms. The aim of the work is to clarify the role of psychological factors in the development, experience, and management of the syndrome. The theoretical part integrates current knowledge on tetany syndrome, stress models, coping strategies, emotion regulation, and personality characteristics, particularly trait anxiety, perfectionism, and high sensitivity. The empirical part employs a sequential mixed-methods design. Based on a qualitative analysis of interviews with patients diagnosed with tetany syndrome, a model was developed describing the relationships among dispositional factors, coping, symptom intensity, and quality of life. This model was subsequently tested on a sample of 735 individuals using structural equation modelling. The findings highlighted symptom intensity as a key predictor of quality of life and confirmed the protective role of acceptance, whereas maladaptive, avoidance-oriented coping strategies were associated with greater symptom severity and poorer quality of life. The monograph contributes to a deeper understanding of the psychological mechanisms underlying tetany syndrome and presents an integrative model of its functioning.